Single method
SV-AUC Study
Sedimentation velocity AUC
Solution-state species distribution, oligomer or aggregation trends, and orthogonal follow-up to SEC.
01 / Services
Peptide characterization services
Choose single-method testing or a combined characterization study for GLP-1 and related metabolic peptides. We confirm the study question, controls and reporting scope with you.
Request a Technical Assessment02 / Service packages
Individual methods and integrated studies
Single method
CD Study
Circular dichroism, far- & near-UV
Compare spectral profiles between test and reference samples and study formulation or temperature effects.
Single method
cIEF Study
Capillary isoelectric focusing
Measure pI and charge-peak distribution. Compare lots, formulations or stressed samples.
Single method
Bioactivity / Potency Assay
Cell-based luciferase reporter gene assay
Assess responses at GLP-1R, GIPR or GCGR and report relative potency when the reference comparison supports it.
Recommended
Integrated Package
AUC + CD + cIEF + Bioassay, one report
Agree common sample identifiers and comparison conditions, then combine the selected methods, results and study limitations in one report.
Deliverables by method
We confirm the deliverables and reporting range for your sample and scope during technical assessment.
- SV-AUC · Sedimentation coefficient distribution
- c(s) profile
- SV-AUC · Species distribution
- Relative signal fractions for resolved species
- SV-AUC · Sedimentation coefficient
- s20,w (standard conditions)
- SV-AUC · Molecular weight
- Solution-state estimate
- CD · Far-UV (190–250 nm)
- Secondary structure spectrum
- CD · Composition
- α-helix / β-sheet estimate
- CD · Near-UV
- Tertiary structure fingerprint
- CD · Thermal transition
- Apparent transition temperature, where suitable
- cIEF · Isoelectric point
- pI determination
- cIEF · Charge variants
- Acidic / basic variant ratios
- cIEF · Peak distribution
- Relative peak areas with integration notes
- Report · Interpretation
- Integrated cross-method analysis
- Bioassay · Dose response and potency
- Fitted curve parameters and relative potency where suitable
- Bioassay · Receptor panel
- GLP-1R / GIPR / GCGR CRE-luciferase
- Report · Data package
- Methods, raw data, figures
- Report · Documentation
- Applicable guidance and project records, as agreed
- Study design · Formulation
- Buffer / excipient screening
- Study design · Comparability
- Pre/post-change protocols
Related molecule guides
Discuss your sample and study goals
Share the molecule name or code, sample format, concentration, buffer and the question you want to answer. We can discuss the method, sample amount, reporting scope and timeline.
Request a Technical Assessment